Instrumentation

Lab Instrumentation

Thermo Scientific LTQ FT Hybrid Mass Spectrometer

  • Dual ion trap and 7 Tesla Fourier transform ion cyclotron resonance detection systems
  • 100,000 resolution a 400 m/z (@ 1 sec acquisition)
  • 500,000 maximum resolution (broadband mode)
  • Sub-1ppm accuracy with internal calibration

Bruker Daltonics MaXis Impact

  • Ultra-high resolution quadrupole time of flight (qTOF) mass spectrometer
  • 40,000 resolution and sub-1ppm mass accuracy w/ internal calibration

Bruker Daltonics Autoflex Speed

  • MALDI-TOF mass spectrometer with high speed (2kHz) laser
  • Linear and reflectron detection modes; reflectron mode can achieve up to 15,000 resolution.


Bruker Daltonics MicrOTOF-QII

  • High resolution quadrupole time of flight (qTOF) mass spectrometer
  • 17,500-20,000 resolution and 1-2ppm mass accuracy w/ internal calibration

(X2) Bruker Daltonics AmaZon ETD Ion Trap

  • Ion trap with collision induced dissociation (CID) and electron-transfer dissociation (ETD) fragmentation capabilities
  • High-speed acquisition up to 20 Hz spectral repetition rate

Bruker Daltonics Microflex

  • Matrix assisted laser desorption ionization time of flight (MALDI-TOF) mass spectrometer
  • Linear detection mode and high resolution reflectron detection mode (up to 10,000 resolution)

Thermo TSQ800EVO Triple Quadrupole GC/MS

  • Triple quadrupole mass spectrometer capable of high-sensitivity detection of over 1000 compounds in a single run
  • Electronic impact (EI) and chemical ionization (CI) capabilities
  • TriPlus RSH Autosampler allows for standard injections, headspace sampling, and solid phase microextraction

Thermo qExactive Hybrid Quadrupole-Orbitrap

  • High resolution quadrupole-orbitrap capable of esolving power up to 140,000 FWHM.
  • Maximum scan rate of 12Hz
  • 1ppm accuracy with internal calibration

Thermo TSQ Quantum Access Max Triplequadrupole LC/MS

  • Triple quadrupole ESI mass spectrometer capable of detection & quantitation of up to 3000 defined compounds per run
  • High-speed 25msec positve/negative polarity switching

Mass Spectrometer Peripherals

Advion Nanomate Triversa

  • Chip-based nano-electrospary ionization source with thermostated sample holder
  • Mountable on Thermo Scientific LTQ-FT-ICR

Advion Nanomate 100

  • Chip-based nano-electrospary ionization source
  • Mountable on Thermo Scientific LTQ-FT-ICR

Microscope-coupled Ambient Electrospray Ionization Mass Spectrometry Interface

  • Inverted light microscope with fluorescence capabilities
  • Mountable on Thermo Scientific LTQ-FT-ICR

Prosolia Flowprobe

  • Liquid-microjunction surface sampling probe (LMJ-SSP)
  • Mountable on Thermo Scientific LTQ-FT-ICR

Bruker Daltonics FAIMS-Mass Spectrometry Interface

  • High-field asynchronous ion mobility spectroscopy (FAIMS) mass spectrometry interface for gas-phase separation of ions generated via electrospray ionization
  • Mountable to Bruker Daltonics Maxis Impact

Prosolia DESI -2D Source for Bruker ESI Instruments

  • Automated desorption electrospray ionization (DESI) source
  • Mountable on all Bruker ESI mass spectrometers

(X2) Bruker Daltonics Captive Spray

  • Nano-electrospray capillary LC/MS source
  • Mountable on all Bruker ESI mass spectrometers

Bruker Daltonics Image Prep

  • MALDI matrix deposition device for MALDI imaging

HPLCs/UPLCs

Agilent Infinity 1200 HPLC

  • Quaternary pump (400 bar max. pressure) with 4 channel in-line degasser
  • Multiple wavelength UV-Vis detector
  • Stand-alone instrument

Agilent Infinity 1260 HPLC

  • Quaternary pump (600 bar max. pressure) with 4 channel in-line degasser
  • Diode array UV detector
  • Temperature controlled column compartment
  • Analytical scale fraction collector
  • Coupled to Bruker Daltonics AmaZon ETD

Agilent Infinity 1290 UHPLC

  • Binary pump (1000 bar max. pressure) with 2 channel in-line degasser
  • Autosampler with thermostated sample holder
  • Temperature controlled column compartment
  • Coupled to Bruker Daltonics MicrOTOF-QI

2x Thermo Dionex Ultimate 3000 UHPLC

  • Binary pump (1000 bar max pressure)
  • Carousel autosampler
  • Temperature controlled column compartment
  • Coupled to Bruker Daltonics MaXis Impact

Thermo Dionex Vanquish UHPLC w/ Charger

  • Binary pump (1400 bar max pressure)
  • Charger automated plate handler capable of automatically loading 20 96-well plates into carousel
  • Thermostatted 4-position carousel autosampler
  • Temperature controlled column compartment
  • Coupled to qExactive and TSQ Access Max

Thermo Scientific Surveyor HPLC

  • Binary pump (400 bar max pressure)
  • Thermostated autosampler
  • Temperature controlled column compartment
  • Coupled to Thermo Scientific LTQ-FT-ICR MS

General Items

Labconco Freezone -105 °C 4.5 liter freeze dry system

  • With Labconco Centrivap centrifugal vacuum concentrator
  • With Vacuumbrand hybrid (diaphragm/rotary) vacuum pump

Labconco Purifier Class II Safety Cabinet

Eppendorf MasterCycler Gradient PCR Thermal Cycler

New Brunswick Scientific Excella E25 Incubator Shaker

Sorvall Legend RT High Capacity Benchtop Centrifuge

BioTek Precision Microplate Sample Processor & Pipetting System

Alpha Innotech AlphaImager HPGgel Imaging System

Bucci Rotavapor R-3 rotory evaporator

  • With KNF Neuberger diaphragm pump (34 L/min, 6 Torr)

(X2) Fisher Scientific Isotemp Laboratory Incubator